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Medicinal Importance Of Glycyrrhiza Glabra

Ayurveda Nov, 2022

Plants have been one of the important sources of medicines since the beginning of human cultivation. There is a growing demand for plant based medicines, health products, pharmaceuticals, food products, cosmetics etc. 

A review of chemical constituents present in various parts of Glycyrrhiza glabra and their pharmacological actions is given in the present article. Glycyrrhiza glabra Linn, is a commonly used herb in Ayurvedic medicine. 

Although the review articles on this plant are already published, this review article is presented to comply all the updated information on its phytochemical and pharmacological activities, which were performed by widely different methods.

Studies indicate that Glycyrrhiza glabra Linn possesses antibacterial, antioxidant, antimalarial, antispasmodic, antiinflammatory and anti-hyper glycemic properties. 

Various other effects like antiulcer, antiviral, antihepatotoxic, antifungal and herpes simplex have also been studies. These results are very encouraging and indicate this herb should be studies more extensively to confirm these results and reveal other potential therapeutic effects. 

A review of chemical constituents present in various parts of Glycyrrhiza glabra and their pharmacological actions is given in the present article.

Glycyrrhiza glabra L. (Licorice) is a small perennial herb that has been traditionally used to treat many diseases, such as respiratory disorders, hyperdipsia, epilepsy, fever, sexual debility, paralysis, stomach ulcers, rheumatism, skin diseases, hemorrhagic diseases, and jaundice. 


Moreover, chemical analysis of the G. glabra extracts revealed the presence of several organic acids, liquirtin, rhamnoliquirilin, liquiritigenin, prenyllicoflavone A, glucoliquiritin apioside, 1-metho-xyphaseolin, shinpterocarpin, shinflavanone, licopyranocoumarin, glisoflavone, licoarylcoumarin, glycyrrhizin, isoangustone A, semilicoisoflavone B, licoriphenone, and 1-methoxyficifolinol, kanzonol R and several volatile components. 

Pharmacological activities of G. glabra have been evaluated against various microorganisms and parasites, including pathogenic bacteria, viruses, and Plasmodium falciparum, and completely eradicated P. yoelii parasites.

Additionally, it shows antioxidant, antifungal, anticarcinogenic, anti-inflammatory, and cytotoxic activities. 

The current review examined the phytochemical composition, pharmacological activities, pharmacokinetics, and toxic activities of G. glabra extracts as well as its phytoconstituents. 

Glycyrrhiza glabra (family Fabaceae), commonly known as licorice, is a herbaceous perennial that has been used as a flavoring agent in foods and medicinal remedies for thousands of years. 

Licorice root has been widely used around the world to treat cough since ancient times. It was used traditionally for treating a variety of conditions, including lung, liver, circulatory, and kidney diseases. 

Today, licorice root is promoted as a Ayurvedic product for conditions such as digestive problems, menopausal symptoms, cough, and bacterial and viral infections.

G. glabra is an herbal plant which has lots of medicinal properties such as antimicrobial, antioxidant, anti-inflammatory, antitussive, antidiabetic, antiviral, anticancer, antimutagenic, antiulcer, and hepatoprotective. The phytochemicals present in G Licorice. 

Licorice is the extract of Glycyrrhiza glabra roots and is often used in ancient Siddha medicine and is approved by the German commission. Licorice is used for gastritis, cough, bronchitis, ulcers, inflammation, and epilepsy. 62. 

The association between the use of licorice and hypertension is well established ... Licorice is an herb that grows in parts of Europe and Asia. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. 


The chemicals in licorice are thought to decrease swelling, decrease cough, and increase the chemicals in our body that heal ulcers. Many "licorice" products made in the U.S. actually don't contain licorice. 

They contain anise oil, which has the smell and taste of "black licorice". Licorice is used for eczema, swelling of the liver, mouth sores, and many other conditions, but there is no good scientific evidence to support most of these uses. 

There is also no good evidence to support using licorice for COVID-19. Glycyrrhiza glabra L. (Family: Fabaceae) is a small perennial herb, commonly known as licorice, sweet wood, or mulaithi, that is indigenous to Eurasia, northern Africa, and western Asia

The Glycyrrhiza genus is widely distributed worldwide and it consists of more than 30 species. Its name was obtained from the Grecian words glykys, which means sweet, and rhiza, which means root, while the glabra species name refers to the smooth husks and is acquired from the Latino word glaber that implies bare or slick

G. glabra is a 1 m tall herbaceous plant that consists of 9–17 leaflets and 7–15 cm long pinnate leaves, with pale whitish blue to purple flowers with a length ranging from 0.8 to 1.2 cm. 

The fruits are 2–3 cm long oblong pods, containing several seeds with stoloniferous roots Licorice grows near a river or stream in fertile, clay, or sandy soil, where there is water available for the plant to flourish Rhizomes and roots are the most important medicinal parts of licorice that have been reported to be used alone or with other herbs for the treatment of many digestive system disorders (e.g., stomach ulcers, hyperdipsia, flatulence, and colic), respiratory tract disorders, such as coughs, asthma, tonsillitis, and sore throat, epilepsy, fever, sexual debility, paralysis, rheumatism, leucorrhoea, psoriasis, prostate cancer, malaria, hemorrhagic diseases, and jaundice. Moreover, it can be used as a food and beverage flavoring agent and added to flavor tobacco product. 

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Author: Khairunnisa Kagzi

MBDH Wellness has more than 60 years of knowledge, and research on Ayurvedic Health Products. We strictly follow the principles of Ayurvedic philosophy and have helped thousands of customers who are looking for traditional Ayurvedic medicines for ailments and treatments. 

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